America Business Spotlight 2023: Collagen Native Type 2

Collagen Native Type 2 Manufacturing

If you have been following us, we recently posted on the Made in America Blog and highlighted why buying products that are made in America today is a smart choice.  Today we would like to highlight the background of SBEDGE® Supplement’s Collagen Native Type 2 and lay out our experience and qualifications.


 Sioux Biochemical started in 1995 with the isolation of proteins and hormones for research.  This included ovine, bovine and porcine Follicle Stimulating hormone (FSH), Luteinizing Hormone (LH), Growth Hormone (GH), Adrenocorticotropic Hormone (ACTH), Prolactin (Luteotropic Hormone), and Thyroid Stimulating hormone (TSH).

This also included enzymes and research proteins such as Gonadotropin Releasing Hormone (GnRH), Human Chorionic Gonadotropin (hCG), Pregnant Mare Serum Gonadotropin (PMSG; eCG), Secretin and chogcrystokinin, Trypsin, and Chymotrypsin. 

 Additionally, we have…

·         Developed a process for the extraction and purification of Chondroitin Sulfate (CS) from bovine trachea.  This led to the creation of a secondary sister company called Sioux Pharm which was dedicated to the production of CS.

·         Worked with several clients on the development of extraction of proteins from GMO crops, such as Corn and Rice.  The companies we worked with created a GMO crop with a protein of interest inserted into the genetics of the crop.  The protein(s) were difficult to attain from other methods.  Extraction, purification and stabilizing of the proteins were often required.

·         Developed a process for the manufacture of Biodiesel from sources such as corn oil and other agricultural/plant sources.  This project lasted for 3 years until the sourcing of feed stock became too competitive to continue, but Sioux Bio was considered to have some of the highest quality Bio Diesel available.

Finally, and most recently Sioux Bio has worked on the isolation of an undenatured type 2 collagen from bovine source for the supplement market that it branded under SBEDGE® Supplements name.


Our process starts with raw bovine material that comes 100% from USDA-inspected facilities right here in the United States.  Then our gentle extraction process allows our collagen to retain the characteristics of the Full Molecule in its natural form.  This is important since it becomes bio-active in nature allowing your body to process it naturally, which then triggers other important biological processes in your body.

You can learn more about Dr. Kramer and SBEDGE® Supplements and its Collagen product by visiting their website.  And don’t forget to check out their 90-Day Collagen Challenge.

Many thanks to Dane the Hibma, Plant Engineer at SB EDGE, with over 7 years of experience in Collagen manufacturing.

3 Reasons You Should Inspect Industrial Equipment That Isn’t Broken

Inspecting Your Industrial Equipment

A couple of weeks ago, Amanda Clark noticed that a service crew had installed new racking in our warehouse. At first, I was a little confused by this. What's wrong with our current racking? Why did we need to get new racking? Did something happen that I didn't know about? After asking these questions, I found out that we were just upgrading our racking system. But if it isn't broken....why would we need to fix it?

In this day and age, it is a good idea to inspect all of your current equipment, even if it “visually appears to be ok” and consider fixing or replacing it with new equipment. The cost of inspecting or having everything checked is nominal compared to have the equipment break or fail completely. Not just the cost of replacement but the related costs of employee injuries or damage to your building or products is far more expensive that  taking time to see if there is a need to fix and replace.

Everyone’s workplace is different and so equipment is subjected to a variety of environments that can accelerate the life expectancy of equipment. It can also become outdated because newer technology or materials may have made such an improvement the replacement will pay for itself. But you will never know until you check.

We came up with three solid reasons why you should consider this.



Just because equipment looks safe on the outside, it doesn’t mean it’s actually safe to use! Racking in particular often gets dinged up by fork trucks and other equipment. This can really affect the structural integrity of the racking system.

You never want to put your employees in a position where they can get injured. So doing racking inspections and having preventative maintenance performed on doors and truck and loading dock equipment is a must!


Newer racking systems and truck and loading dock equipment are built to be more efficient for the end user. One of the reasons we replaced our racking system in our warehouse was because the loading and unloading from the rack was more efficient than the previous racking system. Efficiency leads to happier employees and higher productivity.


It's simple. New equipment that is easier to use will increase your productivity and thus, your profits.

Good and sound advise! Many thanks to Amanda Clark, Marketing Manager, Barron Equipment Company


Advanced Processing with Advanced Injection Molding Machines

Pack Phase – Judge, Jury and Executioner?



You may have heard the old phrase where someone was described as being the “judge, jury and executioner.” Its definition per Wikipedia:

judge, jury and executioner

1.    (idiomatic) Someone with the roles of judgejury and executioner;
someone with full power to judge and punish others unilaterally.

This phrase is used to describe one person or entity as being completely in control over another’s fate – a sole body yielding the power and authority to determine another’s outcome. In injection molding, the PACK portion of plastic injection is often overlooked, but it has the power to control so much – typically more than is often realized.

It has been decades since the injection molding industry underwent a significant and very positive growth in machine and process capabilities. Anymore, at a minimum, two injection stages should be used when molding properly. This 2-stage filling of the mold begins using a constant and typically fast fill rate (FILL) followed by the remainder of fill being completed under constant pressure for a period of time – the very definition of the V►P (velocity to pressure) transfer on your injection molding machines (IMM). Processing this way is called by many names with the most popular being referred to as scientific injection molding or decoupled molding.

Under 2-stage molding, this stage of injection, aside from being called 2nd stage, is commonly referred to as HOLD, PACK, or PACK and HOLD. Even though multiple things are being accomplished, this PACK and HOLD stage is typically a shared set of machine parameters. After V►P, the 2nd stage begins with the final filling of the mold cavity and then the pressurization (or compression) of plastic into the mold cavity – these two things equal the PACK only portion of 2nd stage injection. Next, and without any machine setpoint transition, the true HOLD phase begins. HOLD maintains this 2nd stage plastic pressure setting to help compensate for some of the plastic shrinkage that occurs from the molten plastic solidifying and cooling in the cavity. This continues for a set period of time until the gate has solidified at which point the screw may then be programmed to rotate to prepare the next shot of plastic. It is important to note that as a single setpoint, the 2nd stage pressure is only set to what gives the best balance for many items – filling the part without flashing, yielding the best dimensional results, and more.

3-Stage Injection for Immediate Improvements

Flash, short shots, and dimensional repeatability are some of the most common injection molded part quality issues regularly faced by an injection molder and mold maker. From the tooling side, flash can be the result of poor tooling condition, design and construction (i.e., where flash is present even when intentionally molding a short shot); however, the machine process settings play a very important role with regards to flash as well. So how can we better control our process to help improve upon these everyday issues?

PACK is arguably the most critical stage in an injection molding process, yet it is often combined and “along for the ride” with the HOLD stage. As it would be under any 2-stage injection process, PACK and HOLD are set as one occurring after the V►P transfer. With constant pressure (P) being the control for any injection occurring after this transfer, it is performed with far less control what any injection occurring under constant velocity (V) prior to transfer.

Creating a 3-stage injection process from a 2-stage one means separating PACK into its own stage allowing for the three separate stages (FILL, PACK and HOLD) to each have their own distinct and individually optimized machine settings. The PACK stage now accurately performs the final filling of the mold cavity and establishes the amount of plastic to be compressed into the cavity through a slower, more controlled 2nd injection stage. With PACK moved prior to V►P, its speed (V) and positioning are able to be managed properly. The third stage, HOLD, is now alone after V►P – after the critical quality concerns have been established and managed in process. HOLD is now only a set pressure (P) for a set period of time starting very near to where the final screw forward position will be (i.e., the cushion) doing its job to help maintain the degree of PACK until gate freeze is reached. When implemented properly, significant improvements to scrap, quality, and overall manufacturing efficiencies will be realized throughout your operation.

What’s the Catch?

This change does require another level of processing competency, but it is a much easier jump than making the leap to using in-cavity pressure sensors for control and monitoring of your processes using expensive RJG or Kistler types of technologies. And this change is relatively free. We are heavily invested in the use of in-cavity sensors at Matrix; their merits are well-proven for the high-precision tight-tolerance products we make, but please know you can still make large gains by only investing in the training of your people. This is a “no-brainer” ROI if ever there was one in injection molding, since no large capital expenditure is required.

Matrix received an older, worn transfer mold that had always used a 2-stage injection process. We elected to have this mold serve as our test subject – an imperfect mold to serve as an example to clearly illustrate the differences between 2-stage injection and 3-stage injection. Our experiment on this worn 8-cavity electrical connector mold was performed in our oldest – but still quite capable – 120-ton injection molding machine. I asked our lead process engineer to establish his best 2-stage injection process; as an experienced, degreed plastics engineer who excelled at processing, he set a fundamentally sound process for this tool. We saved shots for evaluation. His process was then adjusted only to separate PACK from HOLD – optimizing each one individually – all of which took between 5-10 minutes. Shots from this 3-stage advanced injection molding process were also saved for evaluation.


The results in our example showed significant improvements from the 3-stage injection process in every measured category. Critical dimensions between circuits in the X and Y directions as well as part flatness were improved by 50%. A limiting factor was that this part had worn steel resulting in excessive flash in the mold’s non-critical void coring areas, something we later rectified in tooling for our customer. As-is, however, parts from the improved process with the highly controlled PACK phase exhibited a flash reduction of nearly 50%. Part weight increased by 0.5%, a significant increase for a thin-walled connector part already exhibiting excessive flash. The increased control allowed for improved pack resulting in a heavier part than before. The denser part shrunk less, and therefore warped less, providing greater dimensional accuracy and stability. Process monitoring over time would have showed the 3-stage process to have less variability and therefore more consistent part quality as well.

Often overlooked, this real-world example shows how the PACK portion of injection holds so much importance and relevance to the quality of molded parts. PACK has the ability to significantly affect the molded product’s outcome with regards to flash, dimensional accuracy and repeatability, and more. Moving forward, this ideological change may be the low hanging fruit that provides immediate and relatively pain-free improvements to your metrics while reducing unnecessary waste in your operation. Your machines are capable, and it isn’t quite the leap you may think it is to implement. I’ve been establishing all processes in this manner for nearly 30 years, and I have yet to find a reason to not start with a 3-stage process and make adjustments from there. Why settle when better is free for the taking and best is a slight process change away?


Tom Moyak

Director of Business and Engineering Development

Matrix Tool, Inc.

4976 Franklin Road

Fairview, PA 16415




About The Author: Tom Moyak is a plastics professional with over 30 years of diverse engineering and manufacturing experience who takes pride in achieving significant increases in quality, efficiency, and profitability through the development of innovative tooling and molding solutions rooted in fundamentals.

Yes, Marketing in the Non-Digital World Still Works

Tips on Effectively Using Yard Signs


We have all seen them, small signs sticking up out of the ground announcing a sale or advertising a service or business. Why in this digital age do we still see yard signs everywhere? It’s simple the idea of yard sign marketing is to grab your attention while out in public. Think about it, have you ever gone to a yard sale or tried a new burger place because you saw a sign while driving or walking down a street.


Most of us react to new stimulus when we are outside of our home or office, when something sticks out and makes an offer that is intriguing it makes us react. Yard signs are not a replacement for digital marketing, radio, or television but then that is not the audience they are going after. Yards signs are to gain the attention of someone here and now. It gets your attention and possibly (if its something you like or are looking for) gets you to act now! There are a lot of assumptions about effectiveness, is it something people are interested, does it offer something I want now, do I have time to stop. But for many, the answer is yes.


So, the concept is to grab someone’s attention and offer them something they would like now. It is important that your yard sign stands out, gets your message out quickly and powerfully, and is easy to read. The biggest mistake people make is trying to put too much information on a sign and using small fonts for your message. A typical yard sign is 18x24” and is the size of a postage stamp to the driver 20-50 feet away. Bright contrasting colors on the background and lettering help the sign stick out from its surroundings. Don’t use muted earth tones on a lawn or tree lined street, you’re trying to get someone’s attention does not blend in with the surroundings.

Thick Simple Message

Font Type, Size and Stroke Thickness all combine to make the words stand out and make the sign easy to read, especially from a distance. Don’t crowd the sign with a lot of text, leave space about the message, phone number and logo so that it again stands out and is clearly readable to your potential audience. Sign messages need to be simple but effective, “WE’RE HIRING” “SALE” “50% OFF” are words that are easily recognized. Web addresses or Facebook addresses are usually too long and need smaller text besides, you want the customer now not when they get home.

Where You Put Them

Finally, is sign positioning, make sure the sign stands out, clear from other distractions like trees, parked cars, or tall weeds. Use your background as a way to frame your advertising message. You will also need to secure the sign to the ground with a wire frame or heavy-duty yard sign stake to keep it from blowing around. You may have to order these separate from the actual signs. Look for sturdy construction, this will help anchor the sign better to the ground and can be re-used for other promotion signs in the future. Look at the thickness and construction of the stakes as it is well worth getting a quality stake that works over seeing your signs knocked to the ground.


Neal Rabogliatti, President, DMS Strategies,

Choosing the Right Industrial Wire Basket

Industrial Wire Baskets - Which One Is The Right One?

The humble industrial wire basket came into existence in the 1890s to help manufacturers move heavy bulk parts easily and efficiently. Over the years baskets became the choice for companies that made stampings, castings, and machined parts because they offer a durable reusable container that can withstand the abuse in a manufacturing plant.


  • Strong construction enables them to handle the loading and unloading of heavy parts.
  • The mesh sides allow liquids (like cleaners or degreasers) to freely flow through the basket and parts and drain easily making operations for parts cleaning more efficient.
  • The open design allows for easy identification of parts inside or for inventory management.
  • The heavy steel construction means they can be reused and subjected to a variety of elements time and time again with needing replacement.
  • The ridged construction allows them to be stacked safety and to reduce valuable floor space.
  • Being made of steel, they allow parts to be heat treated within the container reducing the time to load and upload parts in the process.

What should you look for when buying industrial wire baskets?

This will depend on what type of parts you want to store or move. Not all baskets are the same, in fact there are many options on the market and buying solely on price may not be the best plan.


For heavy, sharp edge parts you need a basket strong enough to withstand the weight and capacity you want. Cheaper thinner wire basket may save some money but are useless if your product causes the sides to bow outward. Be careful about buying collapsible wire baskets for heavier parts, the design allows them to take up less space when not in use, but most don’t offer the integrity for handling large heavy parts.


Space is usually a valuable commodity in a manufacturing plant or warehouse, and baskets can take up a lot of space, that’s why the ability to stack baskets is so important. You need to choose a wire basket that is rigid and strong enough to hold the weight of other baskets on top as well as the capacity and weight of the parts inside. Again, rigid frame baskets offer more strength for stacking than collapsible.


How they are welded

The strength of the frame and mesh sides is important but so is how they are held together. You want to look for wire baskets that are “Weld to Print” and not “Stitch Welded”. Weld to print means the welded seam is a continuous bead from point to point as designated in the design print. Many companies in an effort to reduce costs stitch weld the parts together meaning the weld seams are a series of small welds to secure the seam rather than a continuous one. This shortcut can significantly reduce the integrity of the entire basket because the parts weight or shifting can compromise the weld points and cause the entire basket to break apart resulting in damaged product or worse employee safety.


Size and Capacity

There are many options in the market when it comes to sizes, It is important to determine two factors regarding size when purchasing. First is the size of the parts and the capacity needed to be stored to transported, the inside size. You also must determine the outside size or “footprint” the basket creates so that it can be stored or moved inside your facility easily and not create problems of being too large. You may want to directly contact a metal fabricator to have a basket made to your dimensions and capacities to save money and time in the long run. Once you determine the size and capacity needed, make sure the basket has the strength to handle your parts so that your basket doesn’t break apart or need to be replaced more often.



ESCP is a contract metal fabricator located in Davenport, Iowa. They have built their business on fabricating custom industrial wire baskets, storage racks and shipping containers. They work with your prints or have the relationship with a design agency to design the prints for a custom basket. They have developed a reputation for quality workmanship and manufacture baskets to many OEMs across the country.

Many Thanks to John Nelson from ESCP for providing the information for this post.